Profhilo is manufactured by IBSA (Switzerland) using NAHYCO (Native Hybrid Cooperative Complex) technology — a patented thermal stabilization process that combines high and low molecular weight hyaluronic acid without chemical cross-linking agents. At 64 mg/2 ml, it contains the highest concentration of hyaluronic acid available in any injectable product. This composition gives Profhilo a property unique among injectables: the ability to spread through tissue from just 5 injection points, covering large areas. It activates dermal fibroblasts triggering natural regeneration, stimulating 4 types of collagen (I, III, IV, VII) and 2 types of elastin.

Profhilo is manufactured by IBSA (Switzerland) using NAHYCO (Native Hybrid Cooperative Complex) technology — a patented thermal stabilization process that combines high and low molecular weight hyaluronic acid without chemical cross-linking agents. At 64 mg/2 ml, it contains the highest concentration of hyaluronic acid available in any injectable product. This composition gives Profhilo a property unique among injectables: the ability to spread through tissue from just 5 injection points, covering large areas. It activates dermal fibroblasts triggering natural regeneration, stimulating 4 types of collagen (I, III, IV, VII) and 2 types of elastin.
Dr. Fathi assesses skin laxity, quality, and patient goals to determine whether Profhilo is indicated alone or as part of a combination protocol.
Anaesthetic cream is applied before the session for optimal comfort.
Profhilo is injected using the BAP (Bio Aesthetic Points) technique: 5 anatomically safe injection points per hemiface (10 total for the face), positioned to maximize product diffusion through target tissue while avoiding major facial arteries.
Minor redness and small local swelling at injection points resolve within 24–48 hours. Patients return to normal activities immediately.
Improved hydration, slight increase in radiance
Noticeably firmer skin, improved density
Optimal result: firm, dense, rejuvenated skin
Sustained result with a single maintenance session
First effects from week 1 after session 1; optimal result 4 weeks after session 2
Results last 6 to 9 months; semiannual maintenance session recommended
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Estimated price
Fee upon consultation
Prices shown are estimates and may vary depending on the complexity of your case. A personalized quote will be provided during your consultation.
Profhilo is neither a filler nor a hydration booster. It belongs to an entirely separate category: bio-remodelling injectables. Its mechanism — stimulating fibroblasts to produce collagen and elastin — is fundamentally different from both fillers and skinboosters.
The complete protocol is 2 sessions spaced 4 weeks apart. Improvement begins after the first session, but the optimal result is visible 4 weeks after the second injection.
No. Profhilo significantly improves skin quality and can meaningfully reduce mild laxity, but it cannot correct significant tissue ptosis that requires surgical repositioning.
A complete two-session course typically produces results lasting 6 to 9 months. Semiannual maintenance sessions extend and amplify benefits over time.
With prior application of topical anaesthetic cream, the treatment is very well tolerated. The low injection point count (10 total for the face) means shorter chair time and less cumulative discomfort.
Dr. Fathi generally advises against combining Profhilo and fillers in the same session. A minimum interval of 2–4 weeks between the two is recommended.
Absolutely. Profhilo is equally indicated for men and women. Male patients particularly value the discreet, natural result and the absence of any volumizing effect.
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